This product is a box of 10 vials.
What Is TB-500?
TB-500 is a synthetic version of thymosin beta-4, a 43-amino-acid peptide found in nearly all mammal cells. It helps with cell movement, wound healing, and reducing inflammation. Studies in labs and animals show TB-500 promotes blood vessel growth, speeds up healing, and supports the production of the extracellular matrix, which is important for tissue structure. Researchers are exploring its potential to reduce oxidative stress in spinal cord injuries, aid recovery after heart attacks, and provide anti-aging benefits.
Sequence:Â Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Molecular formula:Â C212H350N56O78S
Molar Mass:Â 4963.4408
CAS number:Â 77591-33-4
PubChem:Â CID 16132341
TB-500 is the active part of thymosin beta-4, which binds to actin, a key protein in cell structure. Actin forms microfilaments that give cells their shape, protect cell membranes, allow cells to move, and help muscles contract. TB-500 helps store actin units so they’re protected and ready to form microfilaments when needed, supporting tissue repair and cell function.
TB-500 and Brain Health
Studies in rats show TB-500 helps repair and rebuild nervous system tissues after injury. It activates cells called oligodendrocytes, which support neurons and promote their growth. This leads to better blood vessel and neuron development in damaged brain areas, improving behavior, movement, and thinking skills. TB-500 also reduces oxidative stress in spinal cord injuries, helping transplanted stem cells survive longer to improve spinal repair. This could be a breakthrough for treating severe spinal cord injuries and helping paralyzed individuals regain movement.
TB-500 and Blood Vessel Growth
TB-500 strongly encourages the growth of small blood vessels, which are vital for healing wounds and growing hair. It supports several steps in blood vessel development, including reshaping the extracellular matrix, forming new blood vessels, and turning basic tissue into the specialized lining of blood vessels. When TB-500 is missing, blood vessel growth and stability suffer, but adding it boosts capillary formation and tissue repair after injury.
TB-500 and Hair Growth
Researchers discovered TB-500’s role in hair growth by chance. Mice lacking thymosin beta-4 grew hair back slowly after shaving, while mice with higher levels of it regrew hair faster. Under a microscope, these mice had more hair shafts and grouped hair follicles, showing TB-500’s potential to support hair growth.
TB-500 and Antibiotic Support
As antibiotic-resistant infections become more common, new solutions are needed. A study in mice with an eye infection showed that TB-500, when combined with the antibiotic ciprofloxacin, improved healing, reduced inflammation, and sped up recovery. After just five days, the combination lowered bacterial counts, reduced white blood cell activity, and decreased harmful oxygen molecules, suggesting TB-500 could enhance antibiotic effectiveness.
TB-500 and Heart Health
Research over the past 20 years shows TB-500 benefits the heart and kidneys through multiple mechanisms. It promotes the growth of backup blood vessels, which helps prevent and recover from disease. It also supports the movement of blood vessel-lining cells and the survival of heart muscle cells after a heart attack. Additionally, TB-500 reduces inflammation and scarring. Recent studies using a gel with TB-500 and collagen showed it boosts blood vessel growth and heart cell movement, aiding recovery after reduced blood flow and reducing long-term scarring.
TB-500 and Brain Diseases
Finding treatments for diseases like Alzheimer’s has been challenging, but TB-500 shows promise. A study found that it boosts autophagy, the brain’s natural defense against neurodegenerative diseases. This could lead to new ways to treat these conditions by enhancing the body’s ability to clear harmful proteins.
TB-500’s Wide Uses
Because TB-500 affects cell structure and function, it has potential in many areas. From treating heart and brain conditions to improving antibiotic effects, it’s a highly studied peptide. Its versatility makes it a key focus for researchers, and it will likely remain so for years to come.
Curious about TB-500 (Thymosin Beta-4)?
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