Kisspeptin, made in the hypothalamus, is an important hormone that starts the release of several other hormones. Also called metastin, this interesting hormone is connected to puberty and may also help stop the spread of cancer.

What does kisspeptin do?

Kisspeptin enters into receptor sites in the pituitary gland, starting a reaction that causes the gland to release neurotransmitters. Those neurotransmitters then signal the release of luteinizing hormone and follicle stimulating hormone. These hormones have a role to play in the production of testosterone and oestradiol. Without kisspeptin, this entire chain reaction would be damaged.

Kisspeptin has a secondary function that is not related to hormones. Its original name, metastin, points to its ability to prevent the spread of cancer in the body.

Kisspeptin is released in conjunction with two other hormones: dynorphin and neurokinin B. These two hormones are not understood well, but early research indicates they may have a role in causing the release of kisspeptin.

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